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Image Number 1014 (Lamellar ichthyosis)

Other Morphologies

Diagnosis: Lamellar ichthyosis

Site: Face

Sex: F

Age: 6

Type: Clinical

Description: Dry scaly face of a twin dhildren (boy and girl).

Submitted by: Nameer Al-Sudany

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Differential Diagnosis


Relative husband and wife having 6 children, four of them were normal and last two babies (twin) delivered as collodion babies, and after shedding, they developed slight generalized erythroderma. Generalized scaling appeared within the first month of life. On examination, the scales were plate-like, large, dark brown and firmly adherent. Deep painful fissures, especially in the digits, palms and soles were also found with a palmoplantar keratoderma. The hair, teeth and mucous membranes were not affected, and growth and intellectual ability were normal. Both children suffered isolation and poor school performance due to the cosmetic appearance.

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