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Image Number 1285 (Pilomatricoma)


Diagnosis: Pilomatricoma

Site: Neck front

Sex: M

Age: 15


Description: Hard nodule.

Submitted by: Nameer Al-Sudany

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Differential Diagnosis

History: Pilomatricoma is the commonest hair follicle-related tumor. It may occur at any age. The majority of patients are under 20 years of age, and females are affected more often than males. The lesion is usually a solitary, deep, dermal or subcutaneous tumor 3–30 mm in diameter situated in the head, neck or upper extremity. The skin over the tumor is normal and the lesion has a firm to stone-hard consistency and a lobular shape on palpation. The diagnosis can be suspected if a subcutaneous nodule feels hard and lobular. The microscopic picture is, however, diagnostic. This patient presented with a hard asymptomatic nodule which has been excised and histologically showed lobules of basaloid cells intermixed with pale pink areas containing ghost cells, a picture characteristic of pilomatricoma.

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