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Image Number 2296 (Ochronosis)


Diagnosis: Ochronosis

Site: Cheek

Sex: F

Age: 25


Description: Dark pigmentation

Submitted by: Ted Rosen

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Differential Diagnosis


Young Hispanic-American who developed melasma during pregnancy. She then applied 10% hydroquinone (obtained outside the United States) twice daily. At first, there was some improvement. Then, she noted the areas started becoming paradoxically darker. The darker the skin became, the more hydroquinone she applied! Biopsy confirmed the diagnosis of exogenous ochronosis.

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