Home | Recent Submissions | Search | Diagnosis | Quiz | Submit an Image | Index | Blog |About GSA
<< Back to Diagnosis Page  
Image Number 2508 (Kyrle disease)


Diagnosis: Kyrle disease

Site: Knee

Sex: F

Age: 45


Description: Keratotic papules at the knee

Submitted by: Ian McColl

View Full Size

Differential Diagnosis


This patient had diabetes and renal failure. She had developed these papules over a period of 12 months. They were itchy.This is Kyrle disease, or acquired perforating dermatosis.The characteristic papules have a keratotic plug made up of neutrophils with eliminated collagen and elastin which is being expelled through the epidermis. It is usually seen on the extensor surfaces of the lower extremities. The condition can completely disappear after renal transplantation.

Search DermNetNZ   eMedicine   PubMed   Dermatology Online   Archives   JAAD for "Kyrle disease "

buy accutane
Home  |  Recent Submissions  |  Search  | Diagnosis  |  Quiz  |  Submit an Image  |  Index  |  About GSA

Copyright © 2005 Global Skin Atlas