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Image Number 2558 (Epidermolysis bullosa congenita)


Diagnosis: Epidermolysis bullosa congenita

Site: Leg

Sex: M

Age: 1


Description: Loose bullae and erosions.

Submitted by: Nameer Al-Sudany

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Differential Diagnosis


Flaccid bullae that rapidly rupture leaving raw erosions have been noticed since first one month of life. The blisters involved mainly the lower limbs specially acral parts but also the face and trunk were also affected. Fortunately, the nails and mucous membranes were spared. Skin biopsy showed skin split within the basal cells of the epidermis. Family history of similar condition was negative.

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