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Image Number 370 (Sweet's Syndrome)

 
Morphology:
Nodule,purple

Diagnosis: Sweet's Syndrome

Site: Wrist

Sex: M

Age: 62

Type: Clinical and Histology

Description: ulcerated nodule on the wrist

Submitted by: Ian McColl

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Differential Diagnosis

History: Sweet's syndrome or Acute Febrile Neutrophilic Dermatosis was first described in 1964 by Dr Robert Sweet.The four subtypes described are 1.  the classic type, 2. that associated with neoplasia, 3. with inflammatory disease and 4. with pregnancy.The plaques and nodules that arise may develope vesiculation or pustules on the surface because of intense dermal edema.This particular patient had ulcerative collitis which had flared recently.The lesions responded rapidly to oral steroids.

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