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Image Number 378 (Xanthelasma)

 
Morphology:
Plaque

Diagnosis: Xanthelasma

Site: Eyelids

Sex: F

Age: 45

Type: Clinical

Description: Yellow plaques

Submitted by: Shahbaz Janjua

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Differential Diagnosis

History: Xanthelasma or xanthoma palpebrarum are yellow plaques that are usually located on the medial side of the upper eyelids.  One half of these lesions have been found to be associated with elevated plasma lipid levels.  Histopathological examination shows xanthelasma to be composed of xanthoma cells which are foamy histiocytes laden with intracellular fat deposits of cholesterol primarily within the upper reticular dermis.

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