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Image Number 414 (Acrodermatitis enteropathica)

 
Morphology:
Erosions

Diagnosis: Acrodermatitis enteropathica

Site: Hands and Feet

Sex: M

Age: 1

Type: Clinical

Description: Large erosions, crusting and eczematous lesions on acral parts

Submitted by: Irfan Bari

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Differential Diagnosis

History: Acrodermatitis enteropathica is an autosomal recessive disease due to a partial disorder of intestinal zinc uptake. Signs usually appear within the first months of life, with a characteristic cutaneous rash that is symmetrical, located around the body orifices, behind the ears, and on hands, feet, and head. Treatment is essentially with dietary or I/V supplementation. Dietary supplementation with 2 – 3 times the recommended daily allowance, 30 – 55 mg/day of elemental zinc dramatically reverses the manifestations within hours to days.

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