| Image Number 441 (Systemic sclerosis) |
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Morphology: Skin coloured,nonscaly
Diagnosis: Systemic sclerosis
Site: Hand,dorsum
Sex: M
Age: 40
Type: Clinical
Description: Sclerosis leading to contractures
Submitted by: Shahbaz Janjua
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Differential Diagnosis
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History: Systemic sclerosis is a systemic connective tissue disorder which affects the connective tissue of the skin and internal organs such as gastrointestinal tract, lungs, heart and kidneys. It is characterized by alterations of the microvasculature, disturbances of the immune system and by massive deposition of collagen.
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