Home | Recent Submissions | Search | Diagnosis | Quiz | Submit an Image | Index | Blog |About GSA
  
<< Back to Diagnosis Page  
Image Number 460 (Linear IgA disease)

 
Morphology:
Blisters

Diagnosis: Linear IgA disease

Site: Thigh

Sex: M

Age: 4

Type: Clinical

Description: Bullae and vesicles on erythematous background

Submitted by: Shahbaz Janjua

View Full Size

Differential Diagnosis

History:

This 4-year-old boy presented with a seven month history of developing a vesiculobullous eruption affecting the lower limbs, the buttocks, and the face. Physical examination revealed mutiple clear round vesicles, bullae and erosions on a marked erythematous back ground. Many of the bullae were arranged to depict the string of pearls and cluster of jewels signs. Oral mucosa was not involved. A tzank smear and gram stain were negative. Other tests are pending. His treatment consisted of dapsone and prednisolone. Linear IgA dermatosis also known as chronic bullous disease of childhood, is a rare, autoimmune subepidermal vesiculobullous disease that may be idiopathic or drug-induced. It is most common in the non reproductive years, so it has a bimodal age of onset. It is histopathologically characterized by the linear deposition of IgA at the basement membrane zone.



Search DermNetNZ   eMedicine   PubMed   Dermatology Online   Archives   JAAD for "Linear IgA disease"

buy accutane
Home  |  Recent Submissions  |  Search  | Diagnosis  |  Quiz  |  Submit an Image  |  Index  |  About GSA

Copyright © 2005 Global Skin Atlas