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Image Number 4711 (Tuberous sclerosis complex)


Diagnosis: Tuberous sclerosis complex

Site: Face

Sex: M

Age: 20


Description: Angiofibromas

Submitted by: Shahbaz Janjua

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Differential Diagnosis


 Tuberous Sclerosis Complex (TSC) was discovered in the 1880's by a French physician named Bourneville.   TSC is an incurable multisystem genetic disorder which can have a wide range of effects.   The physical symptoms of TSC which often lead to its diagnosis include hamartomaceous lesions of the brain, heart, kidneys, skin, lungs, and eyes, mental retardation, seizures, autism, fibromas of the finger and toenails, pitted teeth, and dermatological lesions.   A variety of dermatological disorders have been correlated to TSC. Some of these include hypomelanotic macules,confetti skin lesionsfacial angiofibromasungual fibromasShagreen's patches, and forehead plaque.

Search DermNetNZ   eMedicine   PubMed   Dermatology Online   Archives   JAAD for "Tuberous sclerosis complex"

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