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Image Number 480 (Subcorneal pustular dermatosis)


Diagnosis: Subcorneal pustular dermatosis

Site: Chest

Sex: F

Age: 72

Type: Clinical

Description: Spreading pustules

Submitted by: Ian McColl

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Differential Diagnosis

History: This condition first described by Sneddon and Wilkinson consists of superficial pustules arranged in annular and serpiginous patterns mainly on the abdomen,axillae and groins.The pustules are sterile.Some cases have an IgA paraproteinaemia.The differential diagnoses are pustular psoriasis,impetigo,superficial fungal infections,acrodermatitis enteropathica and necrolytic migratory erythema from the glucagonoma syndrome.Dapsone and sulfapyridine are effective treatments.

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