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Image Number 487 (Merkel cell carcinoma)

 
Morphology:
Nodule

Diagnosis: Merkel cell carcinoma

Site: Cheek

Sex: M

Age: 75

Type: Clinical and Histology

Description: Pink plaque and nodules on the cheek

Submitted by: Ian McColl

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Differential Diagnosis

History: Merkel cell carcinoma can be seen with many different morphologies.These include scaly papules and nodules simulating SCCs and also infiltrated plaques and nodules simulating BCCs or metastases.The ;esionsmay be pink coloured or violaceous.The lesions are rapid growers and are usually seen in individuals with severely sun damaged skin.The tumour is probably better named as primary neuroendocrine carcinoma of the skin.It favours the head and neck regions and metastasizes early.

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