Home | Recent Submissions | Search | Diagnosis | Quiz | Submit an Image | Index | Blog |About GSA
<< Back to Diagnosis Page  
Image Number 810 (Vohwinkel syndrome)


Diagnosis: Vohwinkel syndrome

Site: Foot,dorsum

Sex: F

Age: 30

Type: Clinical

Description: Star shaped keratotic plaques, constricting bands of the digits, and pseudoainhum

Submitted by: Shahbaz Janjua

View Full Size

Differential Diagnosis

History: Vohwinkel syndrome is a rare autosomal dominant disorder of keratinization, characterized by diffuse honeycomb pattern palmoplantar keratoderma, constricting bands of the digits with pseudo-ainhum, and starfish-shaped hyperkeratotic plaques on the dorsum of the hands and feet, elbows, and knees.  Two mutations of the epidermal differentiation complex (a missense mutation of the GJB2 gene coding connexin-26 on chromosome 13, and an insertional mutation of the loricrin gene on the epidermal differentiation complex on 1q21) have been described to be responsible for Vohwinkel syndrome. 

Search DermNetNZ   eMedicine   PubMed   Dermatology Online   Archives   JAAD for "Vohwinkel syndrome "

buy accutane
Home  |  Recent Submissions  |  Search  | Diagnosis  |  Quiz  |  Submit an Image  |  Index  |  About GSA

Copyright © 2005 Global Skin Atlas