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Image Number 861 (Necrobiosis Lipoidica Diabeticorum, NLD)

 
Morphology:
Papules,yellow

Diagnosis: Necrobiosis Lipoidica Diabeticorum, NLD

Site: Shins

Sex: M

Age: 55

Type: Clinical

Description: well-demarcated, asymptomatic yellow-brown atrophic plaques

Submitted by: Ebtisam Elghblawi

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Differential Diagnosis

History:

 

Something like 25 well-demarcated, asymptomatic yellow-brown atrophic plaques with induration and overlying superficial telangiectases were present on the anterior tibial surfaces of the lower extremities.

 

Pathogenesis remains unclear.

 

Necrobiosis lipoidica (NL) is a chronic granulomatous dermatitis that is associated with Type-I diabetes mellitus and less frequently with Type-II diabetes mellitus.

 

The lesions are generally asymptomatic. rarely, pruritus, anesthesia, pain, hypohidrosis, and alopecia at affected sites have been reported. Severe, ulcerative NL may also occur, and it is often refractory to therapy

 

There is no relation between a patient's glycemic control and the likelihood of developing NL lesions, but diabetic patients with NL appear to have higher rates of diabetes-related end-organ damage.



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