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Image Number 942 (Acanthosis nigricans)


Diagnosis: Acanthosis nigricans

Site: Perioral

Sex: F

Age: 27

Type: Clinical

Description: Hyperpigmented plaques

Submitted by: Nameer Al-Sudany

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Differential Diagnosis

History: Acanthosis nigricans is an uncommon condition. The flexures and neck typically show epidermal thickening and pigmentation  and the skin is velvety or papillomatous. Warty lesions are seen around the mouth and on the palms and soles. This lady unfortunately mistakenly was diagnosed as melasma and as perioal  frictional melanosis and recieved many topical preparations with no benefit. She presented with hyperpigmented velvety-like plaques around the mouth area bilaterally and both nasolabial folds for more than one year.

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