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Image Number 965 (Keratoacanthoma)


Diagnosis: Keratoacanthoma

Site: Face

Sex: F

Age: 38

Type: Clinical

Description: Skin-coloured nodule with keratin-filled crator affecting the lower lip of XP woman

Submitted by: Nameer Al-Sudany

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Differential Diagnosis



Xeroderma pigmentosum (XP) is an autosomal recessive disorder characterized by excessive solar damage to the skin that develops at an early age. Consequently, the lesions occur chiefly in areas of the skin habitually exposed to sunlight. At adolescence but sometimes much earlier in the patient's life, various types of premalignant and malignant tumors of the skin appear such as KA, SCC, BCC, malignant melanoma and, rarely, fibrosarcoma.

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