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Image Number 362 (Histoplasmosis)


Diagnosis: Histoplasmosis

Site: Penis

Sex: M

Age: 32

Type: Clinical

Description: Ulcer and swelling of genital skin

Submitted by: Ian McColl

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Differential Diagnosis

History: Histoplasmosis is only rarely a primary skin disease.It is usually seen as a secondary lesion in the skin from pulmonary dissemination in an immunosupressed individual..!0% of theses cases may show erythema nodosum with the pneumonitis..The skin manifestations are many and various including papules,nodules and punched out ulcers.Occassionally pustules and abscesses are the primary skin lesions.The causative organism is Histoplasma capsulatum, a dimorphic fungus present in the soil.Infection is caused by inhalation of the spores from airbourne dusty environments.Amphotericin B is the treatment of choice and Itraconazole can also be used.

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