History:

Eosinophilic fasciitis is a rare skin disease presenting with symmetrical bilateral thickening of the subcutaneous tissues usually involving the limbs with sparing of the face, hands and feet. 

The cause is unknown but may be autoimmune with fascia as the target antigen. It can be triggered by infections, radiation therapy, drugs, underlying malignancy and excessive physical activity. 

There may be blood eosinophilia but a deep incisional biopsy to the fascia will show marked fibrosis of the dermis but also thickened fascia with an infiltrate of eosinophils.

UVA1 and pulsed oral steroids are required to control the disease.

See Dermnet for more details