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Image Number #2234 (Acanthosis nigricans)

Diagnosis: Acanthosis nigricans

Description: Hyperpigmented plaques

Morphology: Hyperpigmentation

Site: Perioral

Sex: F

Age: 27

Type: Clinical

Submitted By: Nameer Al-Sudany

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Differential Diagnosis
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History: Acanthosis nigricans is an uncommon condition. The flexures and neck typically show epidermal thickening and pigmentation  and the skin is velvety or papillomatous. Warty lesions are seen around the mouth and on the palms and soles. This lady unfortunately mistakenly was diagnosed as melasma and as perioal  frictional melanosis and recieved many topical preparations with no benefit. She presented with hyperpigmented velvety-like plaques around the mouth area bilaterally and both nasolabial folds for more than one year.

DermNetNZ   eMedicine   PubMed   Dermatology Online   Archives   JAAD for "Acanthosis nigricans"

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